Therese DePrez was an American production designer.

A native of Rochester, New York, DePrez shared an Art Directors Guild excellence in production design award with four others for their work on the Darren Aronofsky ballet thriller Black Swan, an Oscar nominee for best picture and winner for best actress (Natalie Portman).

Her other film credits include Summer of Sam, Premium Rush, I Shot Andy Warhol, Dark Water, Mr. Magorium’s Wonder Emporium, How to Lose a Guy in 10 Days, and Hedwig and the Angry Inch.

She was the set designer for David Bowie's worldwide Reality Tour in 2003.

DePrez died December 19, 2017, in New York City. She was 52.